CEFAZOLIN (Page 3 of 3)
Reconstitution
Preparation of Parenteral Solution
Parenteral drug products should be SHAKEN WELL when reconstituted, and inspected visually for particulate matter prior to administration. If particulate matter is evident in reconstituted fluids, the drug solutions should be discarded.
When reconstituted or diluted according to the instructions below, Cefazolin for Injection is stable for 24 hours at room temperature or for 10 days if stored under refrigeration (5°C or 41°F). Reconstituted solutions may range in color from pale yellow to yellow without a change in potency.
Single-Dose VialsFor IM injection, IV direct (bolus) injection or IV infusion, reconstitute with Sterile Water for Injection according to the following table. SHAKE WELL.
Administartion
Intramuscular Administration
Reconstitute vials with Sterile Water for Injection according to the dilution table above. Shake well until dissolved. Cefazolin for Injection should be injected into a large muscle mass. Pain on injection is infrequent with Cefazolin for Injection.
Intravenous Administration Direct (bolus) injection: Following reconstitution according to the above table, further dilute vials with approximately 5 mL Sterile Water for Injection. Inject the solution slowly over 3 to 5 minutes, directly or through tubing for patients receiving parenteral fluids (see list below).
Intermittent or continuous infusion: Dilute reconstituted Cefazolin for Injection in 50 to 100 mL of 1 of the following solutions:
Sodium Chloride Injection, USP
- 5% or 10% Dextrose Injection, USP
- 5% Dextrose in Lactated Ringer’s Injection, USP
- 5% Dextrose and 0.9% Sodium Chloride Injection, USP
- 5% Dextrose and 0.45% Sodium Chloride Injection, USP
- 5% Dextrose and 0.2% Sodium Chloride Injection, USP
- Lactated Ringer’s Injection, USP
- Invert Sugar 5% or 10% in Sterile Water for Injection
- Ringer’s Injection, USP
- 5% Sodium Bicarbonate Injection, USP
How Supplied
Cefazolin for Injection, USP is supplied in vials containing cefazolin sodium equivalent to 500 mg or 1 gram cefazolin.
Also available as Pharmacy Bulk Package, as follows:
As with other cephalosporins, Cefazolin for Injection, USP tends to darken depending on storage conditions; within the stated recommendations, however, product potency is not adversely affected.
Before reconstitution protect from light and store at 20° to 25°C (68° to 77°F) [See USP Controlled Room Temperature].
| From Original Manufacturer/Distributor’s NDC and Unit of Sale | To Henry Schein Repackaged Product NDC and Unit of Sale | Total Strength/Total Volume (Concentration) per unit |
| NDC 0143-9923-90Carton of 25 vials | NDC 0404-9835-991 10 mL vial in a bag(Vial bears NDC 0143-9923-90) | 500 mg |
| NDC 0143-9924-90Carton of 25 vials | NDC 0404-9834-991 10 mL vial in a bag(Vial bears NDC 0143-9924-90) | 1 gram |
CLINITEST is a registered trademark of Miles, Inc.
CLINISTIX is a registered trademark of Bayer Corporation.
Manufactured by:
HIKMA FARMACÊUTICA (PORTUGAL) S.A.
Estrada do Rio da Mó, 8, 8A e 8B – Fervença
2705-906 Terrugem SNT PORTUGAL
Distributed by:
Hikma Pharmaceuticals USA Inc.
Berkeley Heights, NJ 07922
Revised: June 2020PIN001-WES/8
Sample Package Label
| CEFAZOLIN cefazolin injection, powder, for solution | |||||||||||||||||
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| Labeler — Henry Schein, Inc. (012430880) |
| Establishment | |||
| Name | Address | ID/FEI | Operations |
| Henry Schein, Inc. | 830995189 | relabel (0404-9834) | |
Revised: 01/2023 Henry Schein, Inc.
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