DERMANIC- niacinamide, inositol niacinate, niacin, chromium nicotinate, folic acid, hydroxocobalamin, ferrous cysteine glycinate and acetylcysteine zinc tablet
Allegis Pharmaceuticals, LLC
Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.
PRESCRIPTION (Rx )-DIETARY SUPPLEMENT
PRODUCT CODE: ++ 28595-500-60
DermaNIC™ is an orally administered, folate-containing prescription (Rx ) dietary supplement for the clinical dietary management of suboptimal niacin and zinc levels associated with acne and/or acne therapy. DermaNIC™ may be administered as adjunctive niacin-folate therapy to provide a protective effect in reducing the risk of hyperhomocysteinemia and/or pellegra in patients undergoing acne therapy or may be administered as monotherapy for patients who are in need of advanced niacin and zinc supplementation as determined by a licensed medical practitioner.2,3,20,22,23 DermaNIC™ is not a drug, but may be prescribed along with acne medications for concomitant care.3 The ultimate goal of acne treatment is to address as many of the pathogenic factors of acne as possible while minimizing side effects.
DermaNIC™ is formulated with niacin and zinc, which support healthful methylation biochemistry and have anti-inflammatory effects via preservation of intracellular coenzyme homeostasis.21 Furthermore, natural ingredients have been added to DermaNIC™ that combine anti-inflammatory and antimicrobial properties along with inhibiting effects on sebum production.22,24-26 Lastly, antibiotic use, which is common in acne patients, can lower the levels of B vitamins that are essential for methylation biochemistry.18 Specifically, studies have shown that acne patients on isotretinoin therapy have decreased folate levels and increased levels of homocysteine.19
|Serving Size: 1 Multiphasic Tablet||Servings Per Container: 60|
|Amount Per Tablet||% DV †|
|Niacin (moiety) from Quadracin™‡||760 mg||3800%|
|moiety comprised of -|| 498 mg from nicotinamide (niacinamide) |
260 mg from inositol nicotinate
1.5 mg from nicotinic acid
0.5 mg from chromium polynicotinate
|Folic Acid, USP as CitraFolic® § [from controlled-release citrated-pteroylmonoglutamic acid]||500 mcg||125%|
|Cobalamin (hydroxocobalamin)||15 mcg||250%|
|Iron (elemental) as AminoFerr® ¶ [from ferrous glycine cysteinate]||1.5 mg||8%|
|Zinc as Zinc-NACx® # [from zinc n-acetyl-l-cysteine]||20 mg||133%|
|Chromium [from chromium polynicotinate]||~70 mcg||58%|
|Inositol [from inositol nicotinate]||~68 mg||Þ|
|N-acetyl-l-cysteine [from zinc n-acetyl-l-cysteine]||49.5 mg||Þ|
Coating (FD&C Yellow No. 6 Lake, FD&C Blue No. 2 Lake, hydroxypropyl methylcellulose, polyethylene glycol, polyvinyl alcohol, titanium dioxide, talc), croscarmellose sodium, magnesium stearate, microcrystalline cellulose, piperine 1, pregelatinized starch, silicified microcrystalline cellulose, silicon dioxide, stearic acid.…. [and other ancillary ingredients 2 as needed to ensure product stability] …
This product contains FD&C Yellow #6 Lake.
- Bioavailability enhancer piperine as BioPerine® is a registered trademark of Sabinsa Corporation, Piscataway, NJ. Protected and manufactured under US Patent Nos. 5,536,506, 5,744,161, 5,972,382; and 6,054,585.
- Since additives, preservatives, bioavailability enhancers, colors and/or flavors of natural origin, etc. are preferred over synthetics, it may be the case that product color, appearance and/or taste may vary slightly over time; and it may be necessary to substitute excipients during the manufacturing process as needed to preserve product appearance and continuity in order to avoid confusion in the marketplace and ensure the highest therapeutic target, safety and quality.
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