Doxycycline hyclate tablets USP, 100 mg are available in light orange colored, round shape, biconvex, film-coated tablets debossed with “141” on one side and “L” on other side containing doxycycline hyclate equivalent to 100 mg doxycycline
NDC 62332-353-20 Bottle of 20 tablets
NDC 62332-353-50 Bottle of 50 tablets
NDC 62332-353-71 Bottle of 500 tablets
Store at 25°C (77°F); excursions permitted to 15° to 30°C (59° to 86°F) [see USP Controlled Room Temperature]. Dispense in tight, light-resistant containers (USP).
Hyperpigmentation of the thyroid has been produced by members of the tetracycline class in the following species: in rats by oxytetracycline, doxycycline, tetracycline PO4 , and methacycline; in minipigs by doxycycline, minocycline, tetracycline PO4 , and methacycline; in dogs by doxycycline and minocycline; in monkeys by minocycline.
Minocycline, tetracycline PO4 , methacycline, doxycycline, tetracycline base, oxytetracycline HCl, and tetracycline HCl were goitrogenic in rats fed a low iodine diet. This goitrogenic effect was accompanied by high radioactive iodine uptake. Administration of minocycline also produced a large goiter with high radioiodine uptake in rats fed a relatively high iodine diet.
Treatment of various animal species with this class of drugs has also resulted in the induction of thyroid hyperplasia in the following: in rats and dogs (minocycline); in chickens (chlortetracycline); and in rats and mice (oxytetracycline). Adrenal gland hyperplasia has been observed in goats and rats treated with oxytetracycline.
For more information call Alembic Pharmaceuticals Limited at 1-866-210-9797.
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2. Cziezel AE and Rockenbauer M. Teratogenic study of doxycycline. Obstet Gynecol 1997; 89: 524–528.
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4. Hale T. Medications and Mothers Milk. 9th edition. Amarillo, TX: Pharmasoft Publishing, 2000: 225–226.
Alembic Pharmaceuticals Limited
Panelav 389350, Gujarat, India
Alembic Pharmaceuticals, Inc.
750 Route 202, Bridgewater, NJ 08807
| DOXYCYCLINE HYCLATE |
doxycycline hyclate tablet, film coated
|Labeler — Alembic Pharmaceuticals Inc. (079288842)|
|Alembic Pharmaceuticals Limited||650574671||MANUFACTURE (62332-353)|
Revised: 05/2020 Alembic Pharmaceuticals Inc.
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