Hepatic Impairment: Patients with hepatic impairment should be closely monitored for toxicity. As chlorambucil is primarily metabolized in the liver, dose reduction may be considered in patients with hepatic impairment when treated with LEUKERAN. However, there are insufficient data in patients with hepatic impairment to provide a specific dosing recommendation.
LEUKERAN is supplied as brown, film-coated, round, biconvex tablets containing 2 mg chlorambucil in amber glass bottles with child-resistant closures. One side is engraved with “GX EG3” and the other side is engraved with an “L.”
Bottle of 25 (NDC 69784-610-25)
Store in a refrigerator, 2° to 8°C (36° to 46°F).
1. NIOSH Alert: Preventing occupational exposures to antineoplastic and other hazardous drugs in healthcare settings. 2004. U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, DHHS (NIOSH) Publication No. 2004-165.
2. OSHA Technical Manual, TED 1-0.15A, Section VI: Chapter 2. Controlling Occupational Exposure to Hazardous Drugs. OSHA, 1999. http://www.osha.gov/dts/osta/otm/otm_vi/otm_vi_2.html
3. American Society of Health-System Pharmacists. ASHP guidelines on handling hazardous drugs. Am J Health-Syst Pharm. (2006) 63:1172-1193.
4. Polovich, M., White, J. M., & Kelleher, L.O. (eds.) 2005. Chemotherapy and biotherapy guidelines and recommendations for practice (2nd. ed.) Pittsburgh, PA: Oncology Nursing Society.
Mfd. by: Excella GmbH, Feucht, Germany
Woodward Pharma Services LLC
Wixom, MI 48393 Rev. 04/22
Principal Display Panel
Each tablet contains 2 mg chlorambucil.
Leukeran 2mg 25 ct. Carton
Leukeran 2mg 25 ct. Label
|LEUKERAN chlorambucil tablet, film coated|
|Labeler — Woodward Pharma Services LLC (080406260)|
Revised: 04/2022 Woodward Pharma Services LLC
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