In acute subdeltoid, subacromial, olecranon, and prepatellar bursitis, one intrabursal injection of 1 mL Betamethasone Sodium Phosphate and Betamethasone Acetate Injectable Suspension can relieve pain and restore full range of movement. Several intrabursal injections of corticosteroids are usually required in recurrent acute bursitis and in acute exacerbations of chronic bursitis. Partial relief of pain and some increase in mobility can be expected in both conditions after one or two injections. Chronic bursitis may be treated with reduced dosage once the acute condition is controlled. In tenosynovitis and tendinitis, three or four local injections at intervals of 1 to 2 weeks between injections are given in most cases. Injections should be made into the affected tendon sheaths rather than into the tendons themselves. In ganglions of joint capsules and tendon sheaths, injection of 0.5 mL directly into the ganglion cysts has produced marked reduction in the size of the lesions.
Following intra-articular administration of 0.5 to 2 mL of Betamethasone Sodium Phosphate and Betamethasone Acetate Injectable Suspension, relief of pain, soreness, and stiffness may be experienced. Duration of relief varies widely in both diseases. Intra-articular Injection of Betamethasone Sodium Phosphate and Betamethasone Acetate Injectable Suspension is well tolerated in joints and periarticular tissues. There is virtually no pain on injection, and the “secondary flare” that sometimes occurs a few hours after intra-articular injection of corticosteroids has not been reported with Betamethasone Sodium Phosphate and Betamethasone Acetate Injectable Suspension. Using sterile technique, a 20- to 24-gauge needle on an empty syringe is inserted into the synovial cavity and a few drops of synovial fluid are withdrawn to confirm that the needle is in the joint. The aspirating syringe is replaced by a syringe containing Betamethasone Sodium Phosphate and Betamethasone Acetate Injectable Suspension and injection is then made into the joint.
|Size of Joint||Location||Dose (mL)|
|Very Large||Hip||1 — 2|
|Large||Knee, ankle, shoulder||1|
|Medium||Elbow, wrist||0.5 — 1|
|Small (metacarpophalangeal, interphalangeal) (sternoclavicular)||Hand, chest||0.25 to 0.5|
A portion of the administered dose of Betamethasone Sodium Phosphate and Betamethasone Acetate Injectable Suspension is absorbed systemically following intra-articular injection. In patients being treated concomitantly with oral or parenteral corticosteroids, especially those receiving large doses, the systemic absorption of the drug should be considered in determining intra-articular dosage.
In intralesional treatment, 0.2 mL/cm 2 of Betamethasone Sodium Phosphate and Betamethasone Acetate Injectable Suspension is injected intradermally (not subcutaneously) using a tuberculin syringe with a 25-gauge, 1/2-inch needle. Care should be taken to deposit a uniform depot of medication intradermally. A total of no more than 1 mL at weekly intervals is recommended.
A tuberculin syringe with a 25-gauge, 3/4-inch needle is suitable for most injections into the foot. The following doses are recommended at intervals of 3 days to a week.
|Diagnosis||Betamethasone Sodium Phosphate and Betamethasone Acetate Injectable Suspension Dose (mL)|
Bursitis under heloma durum or heloma molle
|0.25 to 0.5|
|under calcaneal spur||0.5|
|over hallux rigidus or digiti quinti varus||0.5|
|Tenosynovitis, periostitis of cuboid||0.5|
|Acute gouty arthritis||0.5 to 1|
Betamethasone Sodium Phosphate and Betamethasone Acetate Injectable Suspension, 5 mL multiple dose vial; box of one. Inactive ingredients per mL: 7.1 mg dibasic sodium phosphate anhydrous; 3.4 mg monobasic sodium phosphate monohydrate; 0.1 mg edetate disodium; and 0.2 mg benzalkonium chloride as preservative.
SHAKE WELL BEFORE USING.
Store at 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F) [See USP Controlled Room Temperature]. Protect from light.
SHIRLEY, NY 11967
Revised July 2018
Active Ingredient Purpose
Povidone Iodine 10% w/v (9.85% w/w) Antiseptic
- First aid antiseptic to help prevent skin infection in minor cuts, scrapes and burns.
- For preparation of the skin prior to surgery.
- Helps reduce bacteria that can potentially cause skin infections.
- FOR EXTERNAL USE ONLY
- As a first aid antiseptic for more than 1 week.
- In the eyes.
- Over large areas of the body.
- Deep puncture wounds
- Animal bites
- Serious burns
- If irritation and redness develop
- If condition persists for more than 72 hours, consult a physician.
Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center.
Directions Povidone iodine:
Tear at notch, remove applicator, use only once.
As a first aid antiseptic
- clean affected area
- apply 1 to 3 times daily
- may be covered with a sterile bandage, if bandaged let dry.
For preoperative patient skin preparation
- clean area
- apply to operative site prior to surgery using the applicator
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