OMNIPAQUE (Page 4 of 11)

2.6 Intraarticular Dosage and Administration

TABLE 17 ARTHROGRAPHY
PATIENT POPULATION LOCATION CONCENTRATION (mg iodine/mL) VOLUME (mL) DOUBLE CONTRAST/SINGLE CONTRAST
*
Passive or active manipulation is used to disperse the medium throughout the joint space.
Adults Knee * OMNIPAQUE 240 5 to 15 Lower volumes recommended for double-contrast examinations; higher volumes recommended for single-contrast examinations.
OMNIPAQUE 300 5 to 15
OMNIPAQUE 350 5 to 10
Adults Shoulder * OMNIPAQUE 240 3
OMNIPAQUE 300 10
Adults Temporomandibular * OMNIPAQUE 300 0.5 to 1

2.7 Body Cavity Dosage and Administration

Body Cavity Administration — Undiluted OMNIPAQUE Injection

TABLE 18 ENDOSCOPIC RETROGRADE PANCREATOGRAPHY (ERP) ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY (ECRP)
PATIENT POPULATION CONCENTRATION (mg iodine/mL) VOLUME (mL)
Adults OMNIPAQUE 240 10 mL to 50 mL but may vary depending on individual anatomy and/or disease state.
TABLE 19 HYSTEROSALPINGOGRAPHY
PATIENT POPULATION CONCENTRATION (mg iodine/mL) VOLUME (mL)
Adults OMNIPAQUE 240 and 300 15 mL to 20 mL but may vary depending on individual anatomy and/or disease state.
TABLE 20 HERNIOGRAPHY
PATIENT POPULATION CONCENTRATION (mg iodine/mL) VOLUME (mL)
Adults OMNIPAQUE 240 50 mL but may vary depending on individual anatomy and/or disease state.

Body Cavity Administration — Diluted OMNIPAQUE Injection

TABLE 21 VOIDING CYSTOURETHROGRAPHY (VCU) (CAN BE PERFORMED IN CONJUNCTION WITH EXCRETORY UROGRAPHY)
PATIENT POPULATION CONCENTRATION (mg iodine/mL) VOLUME (mL)
Pediatrics The concentration may vary depending upon the patient’s size and age and with the technique and equipment used. OMNIPAQUE injection may be diluted with Sterile Water for Injection. (See Table 22below). OMNIPAQUE injection may be diluted, utilizing aseptic technique, with Sterile Water for Injection to a concentration of 50 mg iodine/mL to 100 mg iodine/mL for voiding cystourethrography. Range:
  • 50 mL to 300 mL of DILUTED OMNIPAQUE at a concentration of 100 mg iodine/mL
  • 50 mL to 600 mL of DILUTED OMNIPAQUE at a concentration of 50 mg iodine/mL.
TABLE 22 PROCEDURE FOR PREPARATION OF DILUTED *OMNIPAQUE INJECTION FOR VCU
Final Iodine Concentration of Diluted Contrast Agent (mg iodine/mL) Volume of OMNIPAQUE 240 (mL) Volume of Sterile Water for Injection (mL) Volume of OMNIPAQUE 300 (mL) Volume of Sterile Water for Injection (mL) Volume of OMNIPAQUE 350 (mL) Volume of Sterile Water for Injection (mL)
*
Dilutions of OMNIPAQUE should be prepared just prior to use and any unused portion discarded after the procedure.
100 100 140 100 200 100 250
90 167 233 289
80 200 275 338
70 243 330 400
60 300 400 483
50 380 500 600

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