Omnitrenidol (Page 8 of 8)
1.9.1 Dosage
SYSTEMIC
The suggested initial dose is 60 mg, injected deeply into the gluteal muscle. Atrophy of subcutaneous fat may occur if the injection is not properly given. Dosage is usually adjusted within the range of 40 mg to 80 mg, depending upon patient response and duration of relief. However, some patients may be well controlled on doses as low as 20 mg or less.
Hay fever or pollen asthma: Patients with hay fever or pollen asthma who are not responding to pollen administration and other conventional therapy may obtain a remission of symptoms lasting throughout the pollen season after a single injection of 40 mg to 100 mg.
In the treatment of acute exacerbations of multiple sclerosis, daily doses of 160 mg of triamcinolone for a week followed by 64 mg every other day for one month are recommended (see PRECAUTIONS: Neuro-Psychiatric).
In pediatric patients, the initial dose of triamcinolone may vary depending on the specific disease entity being treated. The range of initial doses is 0.11 to 1.6 mg/kg/day in 3 or 4 divided doses (3.2 to 48 mg/m2 bsa/day).
For the purpose of comparison, the following is the equivalent milligram dosage of the various glucocorticoids:
Cortisone, 25 | Triamcinolone, 4 |
Hydrocortisone, 20 | Paramethasone, 2 |
Prednisolone, 5 | Betamethasone, 0.75 |
Prednisone, 5 | Dexamethasone, 0.75 |
Methylprednisolone, 4 |
These dose relationships apply only to oral or intravenous administration of these compounds. When these substances or their derivatives are injected intramuscularly or into joint spaces, their relative properties may be greatly altered.
LOCAL
Intra-articular administration: A single local injection of triamcinolone acetonide is frequently sufficient, but several injections may be needed for adequate relief of symptoms.
Initial dose: 2.5 mg to 5 mg for smaller joints and from 5 mg to 15 mg for larger joints, depending on the specific disease entity being treated. For adults, doses up to 10 mg for smaller areas and up to 40 mg for larger areas have usually been sufficient. Single injections into several joints, up to a total of 80 mg, have been given.
Administration
GENERAL
STRICT ASEPTIC TECHNIQUE IS MANDATORY. The vial should be shaken before use to ensure a uniform suspension. Prior to withdrawal, the suspension should be inspected for clumping or granular appearance (agglomeration). An agglomerated product results from exposure to freezing temperatures and should not be used. After withdrawal, triamcinolone acetonide injectable suspension should be injected without delay to prevent settling in the syringe. Careful technique should be employed to avoid the possibility of entering a blood vessel or introducing infection.
SYSTEMIC
For systemic therapy, injection should be made deeply into the gluteal muscle (see WARNINGS). For adults, a minimum needle length of 1½ inches is recommended. In obese patients, a longer needle may be required. Use alternative sites for subsequent injections.
LOCAL
For treatment of joints, the usual intra-articular injection technique should be followed. If an excessive amount of synovial fluid is present in the joint, some, but not all, should be aspirated to aid in the relief of pain and to prevent undue dilution of the steroid.
With intra-articular administration, prior use of a local anesthetic may often be desirable. Care should be taken with this kind of injection, particularly in the deltoid region, to avoid injecting the suspension into the tissues surrounding the site, since this may lead to tissue atrophy.
In treating acute nonspecific tenosynovitis, care should be taken to ensure that the injection of the corticosteroid is made into the tendon sheath rather than the tendon substance. Epicondylitis may be treated by infiltrating the preparation into the area of greatest tenderness.
1.10 HOW SUPPLIED
Triamcinolone Acetonide Injectable SuspensionTriamcinolone Acetonide Injectable Suspension, USP is supplied in vials providing 40 mg triamcinolone acetonide per mL.
40 mg/mL, 1 mL single-dose vial
MCKESSON ALCOHOL PREP PAD- isopropyl alcohol swab
Drug Facts
Active ingredient
Isopropyl Alcohol 70% v/v
Purpose
First Aid Antiseptic
Use
For preparation of the skin prior to an injection
Warnings
- For external use only
- Flammable, keep away from fire or flame
- Do not use with electrocautery procedures
- Do not use in the eyes
- Do not apply to irritated skin
- Stop use if pain, irritation, redness, or swelling occurs, discontinue use and consult a physician.
- Keep out from reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
Directions
- Open packet
- Remove pad
- Apply topically as needed to cleanse intended area. Discard after single use.
Other information
- Store at room temperature 59-86°F (15-30°C)
- Contents sterile in unopened, undamaged package
Inactive ingredients
purified water
Contents:
1 — 50mL 1% Lidocaine HCL (10mg/mL)
1 — 1mL Triamcinolone Acetonide (40mg/mL)
1 — 5cc Syringe w/ 18-22 Gauge 1-1 1/2 in Needle (Draw)
1 — 27 Gauge 1/2 in Needle (Administer)
1 — 3×3 Gauze Sponge Sterile Square
1 — Bandage 1×3 in
4 — Alcohol Prep Pads
Assembled and Distributed by IT3 Medical, LLC
190 E Stacy Road; STE 306-298 Allen, TX 75002-8734
For questions or comments:
info@IT3-Medical.com, www.IT3-Medical.com
PACKAGING-KIT COMPONENTS LABELING
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Labeler — IT3 Medical LLC (079971231) |
Revised: 02/2022 IT3 Medical LLC
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