|Pemetrexed (pem” e trex’ ed) Injection, for intravenous use|
What is Pemetrexed Injection?
Pemetrexed Injection is a prescription medicine used to treat:
Pemetrexed Injection is not for use for the treatment of people with squamous cell, non-small cell lung cancer.
Pemetrexed Injection has not been shown to be safe and effective in children.
|Do not take Pemetrexed Injection: if you have had a severe allergic reaction to any medicine that contains pemetrexed.|
Before taking Pemetrexed Injection, tell your healthcare provider about all of your medical conditions, including if you:
Females who are able to become pregnant :
Your healthcare provider will check to see if you are pregnant before you start treatment with Pemetrexed Injection. You should use effective birth control (contraception) during treatment with Pemetrexed Injection and for 6 months after the last dose. Tell your healthcare provider right away if you become pregnant or think you are pregnant during treatment with Pemetrexed Injection.
Males with female partners who are able to become pregnant should use effective birth control (contraception) during treatment with Pemetrexed Injection and for 3 months after the last dose.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.Tell your healthcare provider if you have kidney problems and take a medicine that contains ibuprofen. You should avoid taking ibuprofen for 2 days before, the day of, and 2 days after receiving treatment with Pemetrexed Injection.
How is Pemetrexed Injection given?
What are the possible side effects of Pemetrexed Injection?
Pemetrexed Injection can cause serious side effects, including:
The most common side effects of Pemetrexed Injection when given alone are:
The most common side effects of Pemetrexed Injection when given with cisplatin are:
● vomiting ● low white blood cell counts (neutropenia)
● swelling or sores in your mouth or sore throat ● low platelet counts (thrombocytopenia)
● constipation ● low red blood cell counts (anemia)
The most common side effects of Pemetrexed Injection when given with pembrolizumab and platinum chemotherapy are:
● tiredness/weakness ● nausea
● constipation ● diarrhea
● loss of appetite ● rash
● vomiting ● cough
● shortness of breath ● fever
Pemetrexed Injection may cause fertility problems in males. This may affect your ability to father a child. It is not known if these effects are reversible. Talk to your healthcare provider if this is a concern for you.
Your healthcare provider will do blood test to check for side effects during treatment with Pemetrexed Injection. Your healthcare provider may change your dose of Pemetrexed Injection, delay treatment, or stop treatment if you have certain side effects.
Tell your healthcare provider if you have any side effect that bothers you or that does not go away.
General information about the safe and effective use of Pemetrexed Injection.
Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet.
What are the ingredients in Pemetrexed Injection? Active ingredient: pemetrexedInactive ingredients: tromethamine, citric acid anhydrous, methionine and water for injection.
Manufactured In Romania By: Sindan Pharma SRL , Bucharest 1, Romania 011171Manufactured For: Teva Pharmaceuticals , Parsippany, NJ 07054For more information, call Teva at 1-888-838-2872.
This Patient Information has been approved by the U.S. Food and Drug Administration. Rev. A 12/2022
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