Symptoms: Exceeding the recommended dose in patients with normal renal function or administering the recommended dose to patients with impaired renal function (common in elderly patients) may lead to increased serum levels and toxic reactions. Methemoglobinemia generally follows a massive, acute overdose. Methylene blue, 1 to 2 mg/kg/dose given i.v. as a 1% solution as needed, should cause prompt reduction of the methemoglobinemia and disappearance of the cyanosis which is an aid in diagnosis. Oxidative Heinz body hemolytic anemia also may occur, and “bite cells” (degmacytes) may be present in a chronic overdosage situation. Red blood cell G-6-PD deficiency may predispose to hemolysis; however, hemolysis may occur at normal doses in patients with G-6-PD Mediterranean.
Renal toxicity and occasional failure and hepatic impairment may also occur.
Treatment: Treatment is symptomatic and supportive.
Adults: 200 mg 3 times daily after meals. When used concomitantly with an antibacterial agent for the treatment of a urinary tract infection, the administration of phenazopyridine should not exceed 2 days. If symptoms persist, the patient should be re-evaluated.
NDC: 50436-0450-1 9 TABLET in a BOTTLE
| PHENAZOPYRIDINE HCL 100MG |
phenazopyridine hydrochloride tablet
|Labeler — Unit Dose Services (831995316)|
|Unit Dose Services||831995316||REPACK (50436-0450), RELABEL (50436-0450)|
Revised: 12/2018 Unit Dose Services
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